United States health officials are responding to the country’s largest recorded cyclospora outbreak, with federal and state agencies investigating more than 7,400 suspected cases alongside over 4,100 laboratory-confirmed infections as of late July 2026. The outbreak, which began in May 2026, has affected residents in 41 states and has already surpassed the previous national record set in 2019. The Centers for Disease Control and Prevention and the Food and Drug Administration are jointly coordinating investigations into multiple clusters of illness and working with state health departments to track the spread of infections. United States investigators have linked a significant share of the outbreak to iceberg lettuce, prompting Taylor Fresh Foods to initiate a major recall of iceberg lettuce shipped to retail grocery stores and food service establishments in more than two dozen states, including Pennsylvania. The impact of the outbreak has been especially concentrated in the Midwest, with Michigan and Ohio accounting for the vast majority of the 7,400 suspected cases under investigation, and Michigan alone examining 7,171 suspected infections. Confirmed cases have clustered in a five-state region that includes Indiana, Kentucky, Michigan, Ohio, and West Virginia, while Pennsylvania authorities have reported between 30 and 80 confirmed cases, amid varying state criteria for reporting probable and confirmed infections.

Prepared by Olivia Bennett and reviewed by editorial team.