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Rico Dowdle surged to RB2 and remains an RB1, pending a precautionary quad issue. Arizona will start Jacoby Brissett over injured Kyler Murray, lifting Trey McBride and Marvin Harrison amid a pass-happy tilt. Chicago weighs Kyle Monangai’s breakout against D’Andre Swift’s return in a soft Giants matchup. Jacksonville’s injuries open chances for Parker Washington as Jakobi Meyers arrives. Seattle rethinks goal line work and adds deep threat Rashid Shaheed while Sam Darnold attacks downfield. Elsewhere, James Cook’s status clouds Buffalo’s backfield, Garrett Wilson nears a return, Kyren Williams still leads the Rams, and Puka Nacua expects to play.

Prepared by Emily Rhodes and reviewed by editorial team.