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College football's Week 3 predictions feature several key matchups. Darian Mensah is expected to excel passing for Duke against Tulane, while Cam Cook aims for a strong rushing performance for Jacksonville State against Georgia Southern. Bryant Wesco is predicted to lead Clemson's receiving efforts against Georgia Tech. The article also provides predictions for five significant games, including Pitt vs. West Virginia, Georgia vs. Tennessee, South Florida vs. Miami, Texas A&M vs. Notre Dame, and Florida vs. LSU, highlighting key players and anticipated outcomes. An upset is predicted for Minnesota at Cal.

Prepared by Emily Rhodes and reviewed by editorial team.