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NFL waiver wire targets are crucial for Week 6 due to injuries and byes. Top running back additions include Kenneth Gainwell, Kendre Miller, Tyrone Tracy Jr., and Tyjae Spears. Wide receiver Kendrick Bourne is a prime target, especially with San Francisco's injuries. Quarterback Sam Darnold is recommended, with Tua Tagovailoa and Mac Jones also worth considering. Tight end options like Mason Taylor and A.J. Barner are highlighted after strong Week 5 performances. Streamers for DST and kickers are also available to bolster rosters.

Prepared by Emily Rhodes and reviewed by editorial team.