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NFL injury updates reveal several key players facing time off. Eagles' Saquon Barkley is dealing with general knee soreness but is expected to play Thursday. Commanders' Terry McLaurin is optimistic about returning Week 6 from a quad injury. Patriots' Antonio Gibson is out for the season with a torn ACL, while Lions' Terrion Arnold will also miss extended time with a shoulder injury. 49ers' Malik Mustapha is nearing a return from an ACL tear. Colts' kicker Spencer Shrader suffered a season-ending knee injury.

Prepared by Emily Rhodes and reviewed by editorial team.