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Doctors are urging a shift away from diphenhydramine (Benadryl) for allergy treatment, citing safer alternatives like loratadine (Claritin), cetirizine (Zyrtec), and fexofenadine (Allegra). Diphenhydramine's drowsiness and potential for serious side effects, especially in children and the elderly, outweigh its benefits. Experts recommend newer antihistamines due to their superior efficacy and reduced adverse reactions. While the OTC medicine industry notes proper usage instructions, leading allergy specialists are calling for its removal from the market.

Prepared by Olivia Bennett and reviewed by editorial team.