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Researchers used RNA sequencing to identify how exercise impacts specific brain cells in an Alzheimer's model. They found exercise alters gene activity in microglia and a newly identified astrocyte type linked to blood vessels, potentially protecting memory. The metabolic gene Atpif1 was key in promoting new neuron growth. These findings were validated in human brain tissue, suggesting new cell-targeted therapies for Alzheimer's.

Prepared by Olivia Bennett and reviewed by editorial team.