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The 2025 U.S. Open tees off at Oakmont Country Club, with Scottie Scheffler the favorite at +280 odds. Defending champion Bryson DeChambeau (+700), Rory McIlroy (+1100), and Jon Rahm (+1200) are also top contenders. Golf expert Brady Kannon predicts Tommy Fleetwood as a 40-1 longshot, citing his strong season and stats. Kannon also highlights two additional 100-1+ longshots with significant potential for high payouts.

Prepared by Emily Rhodes and reviewed by editorial team.