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Amy Schumer recently showcased her significant weight loss in an Instagram post on October 4th. The 44-year-old comedian appeared noticeably slimmer in a photo with friends Alex Saks and Jillian Bell. Schumer has been open about her weight loss journey, previously sharing a difficult experience with Ozempic due to severe nausea. She has since found success with a combination of hormone replacement therapy for perimenopause and Mounjaro, a GLP-1 drug, which has positively impacted her health and energy levels.

Prepared by Emily Rhodes and reviewed by editorial team.