The San Francisco 49ers will start Mac Jones at quarterback again on Thursday Night Football against the Rams, marking his third start of the season. Brock Purdy is sidelined due to a flare-up of a toe injury sustained earlier, with the team considering him week-to-week. The 49ers will also be without key receivers Ricky Pearsall and Jauan Jennings due to injuries, further impacting their offensive capabilities.

Prepared by Emily Rhodes and reviewed by editorial team.