San Francisco 49ers quarterback Brock Purdy's toe injury continues to be a concern following their Week 4 loss. With a short week before Thursday's game against the Rams, his availability is uncertain, as he was a non-participant in practice. General Manager John Lynch stated Purdy is "questionable," and the team will prioritize his health. If Purdy cannot play, Mac Jones would start, despite his own PCL injury. Wide receiver Ricky Pearsall also sustained a knee injury and is expected to be questionable.

Prepared by Emily Rhodes and reviewed by editorial team.