NFL Week 4 saw key victories for the Kansas City Chiefs, who routed the Ravens with Mahomes leading the offense, and the Buffalo Bills, who remained undefeated. The New York Giants secured their first win with rookie QB Jaxson Dart. The Los Angeles Rams upset the Indianapolis Colts, while the Detroit Lions defeated the Cleveland Browns. Undefeated streaks continued for the Philadelphia Eagles. Other winners included the Jacksonville Jaguars, Pittsburgh Steelers, Houston Texans, Atlanta Falcons, and New England Patriots.

Prepared by Emily Rhodes and reviewed by editorial team.