College football's Week 5 features several key matchups, including undefeated Arizona and Washington facing ranked opponents. Expert picks highlight potential high-yardage performances from several players, such as Josh Hoover (passing), Waymond Jordan (rushing), and Mario Craver (receiving). Five significant games are analyzed, including Ohio State vs. Washington, LSU vs. Ole Miss, and Alabama vs. Georgia. An upset is predicted for Mississippi State against Tennessee. The expert's previous week's picks resulted in a 6-3 record.

Prepared by Emily Rhodes and reviewed by editorial team.