Week 3 of the 2025 NFL season features several key matchups and quarterback controversies. Multiple teams, including the Bengals, 49ers, Jets, and Commanders, face uncertainty at the quarterback position due to injuries. Ten teams are winless entering Week 3, facing pressure to secure their first win. A playoff rematch between the Eagles and Rams, a potential AFC West clash between the Chargers and Broncos, and a Super Bowl preview between the Lions and Ravens highlight the week's action. The games showcase crucial matchups with playoff implications and teams battling early-season adversity.

Prepared by Emily Rhodes and reviewed by editorial team.