Syracuse upset Clemson 34-21, handing the Tigers their worst start under coach Dabo Swinney (1-3). Syracuse quarterback Steve Angeli threw for 244 yards and two touchdowns before a lower leg injury. Justus Ross-Simmons caught two touchdown passes for Syracuse. Clemson's Cade Klubnik threw for 363 yards and three touchdowns but struggled with accuracy. Clemson's poor start and penalties contributed to their defeat. Syracuse's aggressive play-calling and Clemson's self-inflicted errors proved decisive.

Prepared by Emily Rhodes and reviewed by editorial team.