NFL Week 3 features several large betting favorites. The Bills (-12.5) are the biggest favorites, likely to be used by a significant portion of survivor pool contestants despite playing on a short week. Other strong favorites include the Packers (-8) against the Browns, and the Seahawks (-7.5) against the Saints. While the Saints have played competitively, the Seahawks' recent win adds to their appeal for survivor pools. The overall trend shows heavily favored teams continuing to win.

Prepared by Emily Rhodes and reviewed by editorial team.