The San Francisco 49ers trimmed their roster to 53 players, releasing several players including wide receivers Robbie Chosen, Russell Gage, Isaiah Hodgins, and Malik Taylor. Several other players were waived or placed on injured reserve lists. Key wide receivers made the team but are dealing with injuries. The 49ers also moved Brandon Aiyuk to the reserve/PUP list due to an ACL injury, meaning he'll miss the first four games.

Prepared by Emily Rhodes and reviewed by editorial team.