The Detroit Lions will rest approximately 25 players in their preseason game against the Los Angeles Chargers. This includes projected starters like Jared Goff and Amon-Ra St. Brown. The game will offer opportunities for backup and rookie players to showcase their skills, especially in positions like wide receiver and defensive end where many starters are unavailable due to rest or injury. The depth chart reveals several players battling for roster spots, with rookies expected to receive significant playing time. Key players like Hendon Hooker and Roy Lopez may see extended action.

Prepared by Emily Rhodes and reviewed by editorial team.