Choosing the right over-the-counter pain reliever can be confusing. Experts recommend focusing on two main categories: acetaminophen and NSAIDs (nonsteroidal anti-inflammatory drugs). Acetaminophen and NSAIDs work differently, and effectiveness varies depending on the type of pain (headaches, sprains, muscle soreness). The best choice depends on the specific pain experienced.

Prepared by Olivia Bennett and reviewed by editorial team.