Inulin Primes Gut Bacteria to Curb Fructose

A UC Irvine study published in Nature Metabolism reports that inulin, a fiber in onions, garlic, and artichokes, reshapes gut bacteria to consume dietary fructose in the small intestine before it reaches the liver. Researchers led by Cholsoon Jang found that priming microbes with inulin prevented fructose spillover, reduced fat buildup, boosted liver antioxidants, and even reversed signs of fatty liver disease in non-obese participants. The work suggests not all calories are equal and points to personalized nutrition — including targeted prebiotics or probiotics — while exploring whether other fibers offer similar protection.

Reviewed by JQJO team

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